Solvonis Therapeutics
About Solvonis

A clinical-stage psychedelics company developing therapeutics for addiction, PTSD and depression

Solvonis Therapeutics plc (LSE: SVNS) is building an alcohol use disorder franchise across the UK, Europe and the U.S., and a de novo engine of proprietary new medicines.

Strategy

A clinical-stage psychedelics company with two complementary development strategies

Scientific leadership: Professor David Nutt, Chief Scientific Officer, and Edmond J Safra Professor of Neuropsychopharmacology at Imperial College London.

Value-added medicines: the AUD franchise

Differentiated ketamine- and esketamine-based treatments built on established pharmacology, clinical experience and regulatory precedent.

SVN-001 | Phase 3 in severe alcohol use disorder (AUD) in the UK; EU sites proposed
SVN-002 | Esketamine oral thin film (OTF) with an FDA-agreed 505(b)(2) route and a scientific bridge to SPRAVATO®; Phase 2b planning in moderate-to-severe AUD (U.S.)

Value creation | Nearer-term clinical and regulatory catalysts

De novo drug development: the engine

Creating proprietary new chemical entities (NCEs) with composition-of-matter filings in high-burden addiction and psychiatric disorders.

SVN-015 StUD | A new stimulant use disorder candidate; encouraging initial NIDA-funded screening, advanced into further NIDA-funded studies
SVN-114 | A preclinical entactogen for post-traumatic stress disorder (PTSD)
SVN-015 MDD | Depression with anhedonia

Value creation | Longer-duration IP and early-stage upside

Supported by U.S. federal, UK government and academic partners

The SVN-001 Phase 3 is co-funded by the National Institute for Health and Care Research (NIHR), the Medical Research Council (MRC) and Solvonis, and sponsored by the University of Exeter. The U.S. National Institute on Drug Abuse (NIDA) funds the SVN-015 evaluation, which has advanced into further NIDA-funded studies.

Leadership

Leadership combines psychedelic science, public-company execution and commercial experience

Anthony Tennyson
Anthony Tennyson
Chief Executive Officer

Public-company leadership; biopharma capital markets, M&A and psychedelics strategy.

Professor David Nutt
Professor David Nutt
Chief Scientific Officer

Edmond J Safra Professor of Neuropsychopharmacology, Imperial College London; former Chair, UK Advisory Council on the Misuse of Drugs.

Ryan Neates
Ryan Neates
Chief Financial Officer

Public-company finance, governance and capital-markets execution.

Board

Experience across addiction, psychiatry and neurology; biopharma capital markets and M&A; drug development and commercialisation

Dennis Purcell
Dennis Purcell
Chair
Dr Renata Crome
Dr Renata Crome
Non-executive Director
Paul Carter
Paul Carter
Non-executive Director
Nicholas Nelson
Nicholas Nelson
Non-executive Director
Our name

Solvonis: towards freedom

The name Solvonis comes from the Latin root solv-, meaning to release, unbind and free, with a suffix meaning unity.

It reflects what we are working towards: new, effective treatments that free people from debilitating mental health conditions, relieve suffering, and help them reconnect with their families and communities.

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